Agonistic induction of PPARγ reverses cigarette smoke–induced emphysema

The development of emphysema in humans and mice exposed to cigarette smoke is promoted by activation of an adaptive immune response. Lung myeloid dendritic cells (mDCs) derived from cigarette smokers activate autoreactive Th1 and Th17 cells. mDC-dependent activation of T cell subsets requires expres...

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Detalles Bibliográficos
Main Authors: Shan, Ming, You, Ran, Yuan, Xiaoyi, Frazier, Michael V., Porter, Paul, Seryshev, Alexander, Hong, Jeong-Soo, Song, Li-zhen, Zhang, Yiqun, Hilsenbeck, Susan, Whitehead, Lawrence, Zarinkamar, Nazanin, Perusich, Sarah, Corry, David B., Kheradmand, Farrah
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2014
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934169/
https://ncbi.nlm.nih.gov/pubmed/24569375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI70587
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