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Agonistic induction of PPARγ reverses cigarette smoke–induced emphysema
The development of emphysema in humans and mice exposed to cigarette smoke is promoted by activation of an adaptive immune response. Lung myeloid dendritic cells (mDCs) derived from cigarette smokers activate autoreactive Th1 and Th17 cells. mDC-dependent activation of T cell subsets requires expres...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3934169/ https://ncbi.nlm.nih.gov/pubmed/24569375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI70587 |
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