Cigarette Smoke Induction of Osteopontin (SPP1) Mediates T(H)17 Inflammation in Human and Experimental Emphysema

Smoking-related lung diseases are among the leading causes of death worldwide, underscoring the need to understand their pathogenesis and develop new effective therapies. We have shown that CD1a(+) antigen-presenting cells (APCs) from lungs of patients with emphysema can induce autoreactive T helper...

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Detalhes bibliográficos
Main Authors: Shan, Ming, Yuan, Xiaoyi, Song, Li-zhen, Roberts, Luz, Zarinkamar, Nazanin, Seryshev, Alexander, Zhang, Yiqun, Hilsenbeck, Susan, Chang, Seon-Hee, Dong, Chen, Corry, David B., Kheradmand, Farrah
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956594/
https://ncbi.nlm.nih.gov/pubmed/22261033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3003041
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