PB2 mutations arising during H9N2 influenza evolution in the Middle East confer enhanced replication and growth in mammals

Avian influenza virus H9N2 has been endemic in birds in the Middle East, in particular in Egypt with multiple cases of human infections since 1998. Despite concerns about the pandemic threat posed by H9N2, little is known about the biological properties of H9N2 in this epicentre of infection. Here,...

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Vydáno v:PLoS Pathog
Hlavní autoři: Arai, Yasuha, Kawashita, Norihito, Ibrahim, Madiha Salah, Elgendy, Emad Mohamed, Daidoji, Tomo, Ono, Takao, Takagi, Tatsuya, Nakaya, Takaaki, Matsumoto, Kazuhiko, Watanabe, Yohei
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629154/
https://ncbi.nlm.nih.gov/pubmed/31265471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007919
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