H9N2 Influenza Virus Infections in Human Cells Require a Balance between Neuraminidase Sialidase Activity and Hemagglutinin Receptor Affinity

Some avian influenza (AI) viruses have a deletion of up to 20 to 30 amino acids in their neuraminidase (NA) stalk. This has been associated with changes in virus replication and host range. Currently prevalent H9N2 AI viruses have only a 2- or 3-amino-acid deletion, and such deletions were detected...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Arai, Yasuha, Elgendy, Emad Mohamed, Daidoji, Tomo, Ibrahim, Madiha Salah, Ono, Takao, Sriwilaijaroen, Nongluk, Suzuki, Yasuo, Nakaya, Takaaki, Matsumoto, Kazuhiko, Watanabe, Yohei
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7459563/
https://ncbi.nlm.nih.gov/pubmed/32641475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01210-20
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