H9N2 Influenza Virus Infections in Human Cells Require a Balance between Neuraminidase Sialidase Activity and Hemagglutinin Receptor Affinity

Some avian influenza (AI) viruses have a deletion of up to 20 to 30 amino acids in their neuraminidase (NA) stalk. This has been associated with changes in virus replication and host range. Currently prevalent H9N2 AI viruses have only a 2- or 3-amino-acid deletion, and such deletions were detected...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Arai, Yasuha, Elgendy, Emad Mohamed, Daidoji, Tomo, Ibrahim, Madiha Salah, Ono, Takao, Sriwilaijaroen, Nongluk, Suzuki, Yasuo, Nakaya, Takaaki, Matsumoto, Kazuhiko, Watanabe, Yohei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7459563/
https://ncbi.nlm.nih.gov/pubmed/32641475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01210-20
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