Infection of Human Tracheal Epithelial Cells by H5 Avian Influenza Virus Is Regulated by the Acid Stability of Hemagglutinin and the pH of Target Cell Endosomes

Despite the possible relationships between tracheal infection and concomitant infection of the terminal part of the lower respiratory tract (bronchioles/alveoli), the behavior of avian influenza viruses (AIVs), such as H5N1, in the conducting airways is unclear. To examine the tropism of AIVs for ce...

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Veröffentlicht in:Viruses
Hauptverfasser: Daidoji, Tomo, Kajikawa, Junichi, Arai, Yasuha, Watanabe, Yohei, Hirose, Ryohei, Nakaya, Takaaki
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7019350/
https://ncbi.nlm.nih.gov/pubmed/31936692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12010082
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