PB2 mutations arising during H9N2 influenza evolution in the Middle East confer enhanced replication and growth in mammals

Avian influenza virus H9N2 has been endemic in birds in the Middle East, in particular in Egypt with multiple cases of human infections since 1998. Despite concerns about the pandemic threat posed by H9N2, little is known about the biological properties of H9N2 in this epicentre of infection. Here,...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Arai, Yasuha, Kawashita, Norihito, Ibrahim, Madiha Salah, Elgendy, Emad Mohamed, Daidoji, Tomo, Ono, Takao, Takagi, Tatsuya, Nakaya, Takaaki, Matsumoto, Kazuhiko, Watanabe, Yohei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629154/
https://ncbi.nlm.nih.gov/pubmed/31265471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007919
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