Targeted genetic screening in mice through haploid embryonic stem cells identifies critical genes in bone development

Mutagenic screening is powerful for identifying key genes involved in developmental processes. However, such screens are successful only in lower organisms. Here, we develop a targeted genetic screening approach in mice through combining androgenetic haploid embryonic stem cells (AG-haESCs) and clus...

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Spremljeno u:
Bibliografski detalji
Izdano u:PLoS Biol
Glavni autori: Bai, Meizhu, Han, Yujiao, Wu, Yuxuan, Liao, Jiaoyang, Li, Lin, Wang, Lijun, Li, Qing, Xing, Wenhui, Chen, Luonan, Zou, Weiguo, Li, Jinsong
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2019
Teme:
Methods and Resources
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629148/
https://ncbi.nlm.nih.gov/pubmed/31265461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000350
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