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Haploid embryonic stem cells can be enriched and maintained by simple filtration

Mammalian haploid embryonic stem cells (haESCs) serve as a powerful tool for genetic analyses at both the cellular and organismal levels. However, spontaneous diploidization of haESCs limits their use in these analyses. Addition of small molecules to the culture medium to control the cell cycle can...

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Foilsithe in:J Biol Chem
Main Authors: Qu, Chao, Yan, Meng, Yang, Suming, Wang, Lingbo, Yin, Qi, Liu, Yuan, Chen, Yeguang, Li, Jinsong
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892596/
https://ncbi.nlm.nih.gov/pubmed/29449377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002029
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