The VAMP-associated protein VAPB is required for cardiac and neuronal pacemaker channel function

Hyperpolarization-activated cyclic nucleotide–gated (HCN) channels encode neuronal and cardiac pacemaker currents. The composition of pacemaker channel complexes in different tissues is poorly understood, and the presence of additional HCN modulating subunits was speculated. Here we show that vesicl...

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Vydáno v:FASEB J
Hlavní autoři: Silbernagel, Nicole, Walecki, Magdalena, Schäfer, Martin K.-H., Kessler, Mirjam, Zobeiri, Mehrnoush, Rinné, Susanne, Kiper, Aytug K., Komadowski, Marlene A., Vowinkel, Kirsty S., Wemhöner, Konstantin, Fortmüller, Lisa, Schewe, Marcus, Dolga, Amalia M., Scekic-Zahirovic, Jelena, Matschke, Lina A., Culmsee, Carsten, Baukrowitz, Thomas, Monassier, Laurent, Ullrich, Nina D., Dupuis, Luc, Just, Steffen, Budde, Thomas, Fabritz, Larissa, Decher, Niels
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629115/
https://ncbi.nlm.nih.gov/pubmed/29879376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201800246R
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