Antisense oligonucleotide treatment ameliorates IFN-γ–induced proteinuria in APOL1-transgenic mice

African Americans develop end-stage renal disease at a higher rate compared with European Americans due to 2 polymorphisms (G1 and G2 risk variants) in the apolipoprotein L1 (APOL1) gene common in people of African ancestry. Although this compelling genetic evidence provides an exciting opportunity...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:JCI Insight
Main Authors: Aghajan, Mariam, Booten, Sheri L., Althage, Magnus, Hart, Christopher E., Ericsson, Anette, Maxvall, Ingela, Ochaba, Joseph, Menschik-Lundin, Angela, Hartleib, Judith, Kuntz, Steven, Gattis, Danielle, Ahlström, Christine, Watt, Andrew T., Engelhardt, Jeffery A., Monia, Brett P., Magnone, Maria Chiara, Guo, Shuling
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629101/
https://ncbi.nlm.nih.gov/pubmed/31217349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126124
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker