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Protection of abasic sites during DNA replication by a stable thiazolidine protein-DNA crosslink
Abasic (AP) sites are one of the most common DNA lesions that block replicative polymerases. HMCES recognizes and processes these lesions in the context of single-stranded DNA (ssDNA). A HMCES DNA-protein crosslink (DPC) intermediate is thought to shield the AP site from endonucleases and error-pron...
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| Vydáno v: | Nat Struct Mol Biol |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6628887/ https://ncbi.nlm.nih.gov/pubmed/31235915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-019-0255-5 |
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