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Abasic sites preferentially form at regions undergoing DNA replication
We investigated whether apurinic/apyrimidinic (AP/abasic) sites were more frequent in regions of DNA replication in cells and whether their number increased during oxidative stress. DNA fiber spreading and fluorescent immunostaining were used to detect areas of DNA replication and sites of AP lesion...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Federation of American Societies for Experimental Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2996904/ https://ncbi.nlm.nih.gov/pubmed/20511393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-145276 |
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