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Crystallographic snapshots of a replicative DNA polymerase encountering an abasic site
Abasic sites are common DNA lesions, which are strong blocks to replicative polymerases and are potentially mutagenic when bypassed. We report here the 2.8 Å structure of the bacteriophage RB69 replicative DNA polymerase attempting to process an abasic site analog. Four different complexes were capt...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC391061/ https://ncbi.nlm.nih.gov/pubmed/15057283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600150 |
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