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Crystallographic snapshots of a replicative DNA polymerase encountering an abasic site
Abasic sites are common DNA lesions, which are strong blocks to replicative polymerases and are potentially mutagenic when bypassed. We report here the 2.8 Å structure of the bacteriophage RB69 replicative DNA polymerase attempting to process an abasic site analog. Four different complexes were capt...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2004
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC391061/ https://ncbi.nlm.nih.gov/pubmed/15057283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600150 |
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