ATR pathway inhibition is synthetically lethal in cancer cells with ERCC1 deficiency

Por Mohni, Kareem N., Kavanaugh, Gina M., Cortez, David
Publicado em 2014

ATR and ATRIP Are Recruited to Herpes Simplex Virus Type 1 Replication Compartments Even though ATR Signaling Is Disabled

Por Mohni, Kareem N., Livingston, Christine M., Cortez, David, Weller, Sandra K.
Publicado em 2010

DNA Mismatch Repair Proteins Are Required for Efficient Herpes Simplex Virus 1 Replication

Por Mohni, Kareem N., Mastrocola, Adam S., Bai, Ping, Weller, Sandra K., Heinen, Christopher D.
Publicado em 2011

Structure of the Herpes Simplex Virus 1 Genome: Manipulation of Nicks and Gaps Can Abrogate Infectivity and Alter the Cellular DNA Damage Response

Por Smith, Samantha, Reuven, Nina, Mohni, Kareem N., Schumacher, April J., Weller, Sandra K.
Publicado em 2014

Efficient Herpes Simplex Virus 1 Replication Requires Cellular ATR Pathway Proteins

Por Mohni, Kareem N., Dee, Alexander R., Smith, Samantha, Schumacher, April J., Weller, Sandra K.
Publicado em 2013

Herpes Simplex Virus Type 1 Single Strand DNA Binding Protein and Helicase/Primase Complex Disable Cellular ATR Signaling

Por Mohni, Kareem N., Smith, Samantha, Dee, Alexander R., Schumacher, April J., Weller, Sandra K.
Publicado em 2013

A whole genome RNAi screen identifies replication stress response genes

Por Kavanaugh, Gina, Ye, Fei, Mohni, Kareem N., Luzwick, Jessica W., Glick, Gloria, Cortez, David
Publicado no DNA Repair (Amst) (2015)

The HSV-1 Exonuclease, UL12, Stimulates Recombination by a Single Strand Annealing Mechanism

Por Schumacher, April J., Mohni, Kareem N., Kan, Yinan, Hendrickson, Eric A., Stark, Jeremy M., Weller, Sandra K.
Publicado em 2012

The replication checkpoint prevents two types of fork collapse without regulating replisome stability

Por Dungrawala, Huzefa, Rose, Kristie L., Bhat, Kamakoti P., Mohni, Kareem N., Glick, Gloria G., Couch, Frank B., Cortez, David
Publicado no Mol Cell (2015)

Structural Characterization of Interaction between Human Ubiquitin-specific Protease 7 and Immediate-Early Protein ICP0 of Herpes Simplex Virus-1

Por Pozhidaeva, Alexandra K., Mohni, Kareem N., Dhe-Paganon, Sirano, Arrowsmith, Cheryl H., Weller, Sandra K., Korzhnev, Dmitry M., Bezsonova, Irina
Publicado no J Biol Chem (2015)

A Synthetic Lethal Screen Identifies DNA Repair Pathways that Sensitize Cancer Cells to Combined ATR Inhibition and Cisplatin Treatments

Por Mohni, Kareem N., Thompson, Petria S., Luzwick, Jessica W., Glick, Gloria G., Pendleton, Christopher S., Lehmann, Brian D., Pietenpol, Jennifer A., Cortez, David
Publicado no PLoS One (2015)

Enhancer of Rudimentary Homolog Affects the Replication Stress Response through Regulation of RNA Processing

Por Kavanaugh, Gina, Zhao, Runxiang, Guo, Yan, Mohni, Kareem N., Glick, Gloria, Lacy, Monica E., Hutson, M. Shane, Ascano, Manuel, Cortez, David
Publicado no Mol Cell Biol (2015)

An Intrinsically Disordered Region of the DNA repair protein Nbs1 Is a Species-Specific Barrier to Herpes Simplex Virus 1 in Primates

Por Lou, Dianne I., Kim, Eui Tae, Meyerson, Nicholas R., Pancholi, Neha J., Mohni, Kareem N., Enard, David, Petrov, Dmitri A., Weller, Sandra K., Weitzman, Matthew D., Sawyer, Sara L.
Publicado no Cell Host Microbe (2016)