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The HSV-1 Exonuclease, UL12, Stimulates Recombination by a Single Strand Annealing Mechanism

Production of concatemeric DNA is an essential step during HSV infection, as the packaging machinery must recognize longer-than-unit-length concatemers; however, the mechanism by which they are formed is poorly understood. Although it has been proposed that the viral genome circularizes and rolling...

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Autori principali: Schumacher, April J., Mohni, Kareem N., Kan, Yinan, Hendrickson, Eric A., Stark, Jeremy M., Weller, Sandra K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415443/
https://ncbi.nlm.nih.gov/pubmed/22912580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002862
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