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Tunicate Heparan Sulfate Enriched in 2-Sulfated β-Glucuronic Acid: Structure, Anticoagulant Activity, and Inhibitory Effect on the Binding of Human Colon Adenocarcinoma Cells to Immobilized P-Selectin

Heparin or highly sulfated heparan sulfate (HS) has been described in different invertebrates. In ascidians (Chordata-Tunicata), these glycosaminoglycans occur in intracellular granules of oocyte accessory cells and circulating basophil-like cells, resembling mammalian mast cells and basophils, resp...

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Опубликовано в: :Mar Drugs
Главные авторы: Abreu, Wallace S., Soares, Paulo A. G., Motta, Juliana M., Kozlowski, Eliene O., Teixeira, Felipe C. O. B., Soares, Mariana A., Borsig, Lubor, Mourão, Paulo A. S., Pavão, Mauro S. G.
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627333/
https://ncbi.nlm.nih.gov/pubmed/31212795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17060351
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