Tunicate Heparan Sulfate Enriched in 2-Sulfated β-Glucuronic Acid: Structure, Anticoagulant Activity, and Inhibitory Effect on the Binding of Human Colon Adenocarcinoma Cells to Immobilized P-Selectin

Heparin or highly sulfated heparan sulfate (HS) has been described in different invertebrates. In ascidians (Chordata-Tunicata), these glycosaminoglycans occur in intracellular granules of oocyte accessory cells and circulating basophil-like cells, resembling mammalian mast cells and basophils, resp...

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Vydáno v:Mar Drugs
Hlavní autoři: Abreu, Wallace S., Soares, Paulo A. G., Motta, Juliana M., Kozlowski, Eliene O., Teixeira, Felipe C. O. B., Soares, Mariana A., Borsig, Lubor, Mourão, Paulo A. S., Pavão, Mauro S. G.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627333/
https://ncbi.nlm.nih.gov/pubmed/31212795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17060351
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