Tunicate Heparan Sulfate Enriched in 2-Sulfated β-Glucuronic Acid: Structure, Anticoagulant Activity, and Inhibitory Effect on the Binding of Human Colon Adenocarcinoma Cells to Immobilized P-Selectin

Heparin or highly sulfated heparan sulfate (HS) has been described in different invertebrates. In ascidians (Chordata-Tunicata), these glycosaminoglycans occur in intracellular granules of oocyte accessory cells and circulating basophil-like cells, resembling mammalian mast cells and basophils, resp...

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Pubblicato in:Mar Drugs
Autori principali: Abreu, Wallace S., Soares, Paulo A. G., Motta, Juliana M., Kozlowski, Eliene O., Teixeira, Felipe C. O. B., Soares, Mariana A., Borsig, Lubor, Mourão, Paulo A. S., Pavão, Mauro S. G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627333/
https://ncbi.nlm.nih.gov/pubmed/31212795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17060351
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