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Sulfated Hexasaccharides Attenuate Metastasis by Inhibition of P-selectin and Heparanase

Development of compounds that target both heparanase and selectins is emerging as a promising approach for cancer therapy. Selectins are vascular cell adhesion molecules that mediate tumor cell interactions with platelets, leukocytes, and the vascular endothelium. Heparanase is an endoglycosidase th...

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Détails bibliographiques
Auteurs principaux: Borsig, Lubor, Vlodavsky, Israel, Ishai-Michaeli, Rivka, Torri, Giangiacomo, Vismara, Elena
Format: Artigo
Langue:Inglês
Publié: Neoplasia Press Inc. 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084621/
https://ncbi.nlm.nih.gov/pubmed/21532885
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