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New Heparanase-Inhibiting Triazolo-Thiadiazoles Attenuate Primary Tumor Growth and Metastasis

SIMPLE SUMMARY: Heparanase is an endoglycosidase that plays a critical role in tumor progression and metastasis. The expression of heparanase in the tumor microenvironment is positively correlated with the aggressiveness of the tumor and is associated with poor prognosis. In this study, we have demo...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Barash, Uri, Rangappa, Shobith, Mohan, Chakrabhavi Dhananjaya, Vishwanath, Divakar, Boyango, Ilanit, Basappa, Basappa, Vlodavsky, Israel, Rangappa, Kanchugarakoppal S.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8231572/
https://ncbi.nlm.nih.gov/pubmed/34199150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13122959
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