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Control of Hematopoietic Stem and Progenitor Cell Function through Epigenetic Regulation of Energy Metabolism and Genome Integrity

It remains largely unclear how stem cells regulate bioenergetics and genome integrity to ensure tissue homeostasis. Here, our integrative gene analyses suggest that metabolic and genotoxic stresses may underlie the common functional defects of both fetal and adult hematopoietic stem and progenitor c...

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Podrobná bibliografie
Vydáno v:Stem Cell Reports
Hlavní autoři: Yang, Zhenhua, Shah, Kushani, Khodadadi-Jamayran, Alireza, Jiang, Hao
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627005/
https://ncbi.nlm.nih.gov/pubmed/31231026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.05.023
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