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A chromatin perspective on metabolic and genotoxic impacts on hematopoietic stem and progenitor cells

Fate determination in self-renewal and differentiation of hematopoietic stem and progenitor cells (HSCs and HPCs) is ultimately controlled by gene expression, which is profoundly influenced by the global and local chromatin state. Cellular metabolism directly influences the chromatin state through t...

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Detalhes bibliográficos
Publicado no:Cell Mol Life Sci
Main Authors: Yang, Zhenhua, Jiang, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541408/
https://ncbi.nlm.nih.gov/pubmed/32318759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-020-03522-x
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