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A chromatin perspective on metabolic and genotoxic impacts on hematopoietic stem and progenitor cells
Fate determination in self-renewal and differentiation of hematopoietic stem and progenitor cells (HSCs and HPCs) is ultimately controlled by gene expression, which is profoundly influenced by the global and local chromatin state. Cellular metabolism directly influences the chromatin state through t...
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| Published in: | Cell Mol Life Sci |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer International Publishing
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7541408/ https://ncbi.nlm.nih.gov/pubmed/32318759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-020-03522-x |
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