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Hijacking a key chromatin modulator creates epigenetic vulnerability for MYC-driven cancer
While the genomic binding of MYC protein correlates with active epigenetic marks on chromatin, it remains largely unclear how major epigenetic mechanisms functionally impact the tumorigenic potential of MYC. Here, we show that, compared with the catalytic subunits, the core subunits, including DPY30...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6063490/ https://ncbi.nlm.nih.gov/pubmed/29870403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI97072 |
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