Hijacking a key chromatin modulator creates epigenetic vulnerability for MYC-driven cancer

While the genomic binding of MYC protein correlates with active epigenetic marks on chromatin, it remains largely unclear how major epigenetic mechanisms functionally impact the tumorigenic potential of MYC. Here, we show that, compared with the catalytic subunits, the core subunits, including DPY30...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Clin Invest
Egile Nagusiak: Yang, Zhenhua, Shah, Kushani, Busby, Theodore, Giles, Keith, Khodadadi-Jamayran, Alireza, Li, Wei, Jiang, Hao
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2018
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063490/
https://ncbi.nlm.nih.gov/pubmed/29870403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI97072
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