Hijacking a key chromatin modulator creates epigenetic vulnerability for MYC-driven cancer

While the genomic binding of MYC protein correlates with active epigenetic marks on chromatin, it remains largely unclear how major epigenetic mechanisms functionally impact the tumorigenic potential of MYC. Here, we show that, compared with the catalytic subunits, the core subunits, including DPY30...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Yang, Zhenhua, Shah, Kushani, Busby, Theodore, Giles, Keith, Khodadadi-Jamayran, Alireza, Li, Wei, Jiang, Hao
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063490/
https://ncbi.nlm.nih.gov/pubmed/29870403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI97072
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