Lataa...

Hijacking a key chromatin modulator creates epigenetic vulnerability for MYC-driven cancer

While the genomic binding of MYC protein correlates with active epigenetic marks on chromatin, it remains largely unclear how major epigenetic mechanisms functionally impact the tumorigenic potential of MYC. Here, we show that, compared with the catalytic subunits, the core subunits, including DPY30...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Clin Invest
Päätekijät: Yang, Zhenhua, Shah, Kushani, Busby, Theodore, Giles, Keith, Khodadadi-Jamayran, Alireza, Li, Wei, Jiang, Hao
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063490/
https://ncbi.nlm.nih.gov/pubmed/29870403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI97072
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!