N-Myc-induced metabolic rewiring creates novel therapeutic vulnerabilities in neuroblastoma

N-Myc is a transcription factor that is aberrantly expressed in many tumor types and is often correlated with poor patient prognosis. Recently, several lines of evidence pointed to the fact that oncogenic activation of Myc family proteins is concomitant with reprogramming of tumor cells to cope with...

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Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Tjaden, Britta, Baum, Katharina, Marquardt, Viktoria, Simon, Mareike, Trajkovic-Arsic, Marija, Kouril, Theresa, Siebers, Bettina, Lisec, Jan, Siveke, Jens T., Schulte, Johannes H., Benary, Uwe, Remke, Marc, Wolf, Jana, Schramm, Alexander
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188804/
https://ncbi.nlm.nih.gov/pubmed/32346009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64040-1
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