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CCR5 Signaling Promotes Murine and Human Hematopoietic Regeneration following Ionizing Radiation

Hematopoietic stem and progenitor cells (HSPCs) depend on regulatory cytokines from the marrow microenvironment. From an unbiased cytokine screen of murine marrow supernatants, we identified C-C motif chemokine ligand 5 (CCL5) as an endothelial cell-secreted hematopoietic growth factor. Following tr...

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Bibliografski detalji
Izdano u:Stem Cell Reports
Glavni autori: Piryani, Sadhna O., Kam, Angel Y.F., Vu, Uyen T., Chao, Nelson J., Doan, Phuong L.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6626871/
https://ncbi.nlm.nih.gov/pubmed/31155503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.04.023
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