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CCR5 Signaling Promotes Murine and Human Hematopoietic Regeneration following Ionizing Radiation

Hematopoietic stem and progenitor cells (HSPCs) depend on regulatory cytokines from the marrow microenvironment. From an unbiased cytokine screen of murine marrow supernatants, we identified C-C motif chemokine ligand 5 (CCL5) as an endothelial cell-secreted hematopoietic growth factor. Following tr...

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Dades bibliogràfiques
Publicat a:Stem Cell Reports
Autors principals: Piryani, Sadhna O., Kam, Angel Y.F., Vu, Uyen T., Chao, Nelson J., Doan, Phuong L.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6626871/
https://ncbi.nlm.nih.gov/pubmed/31155503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.04.023
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