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CCR5 Signaling Promotes Murine and Human Hematopoietic Regeneration following Ionizing Radiation

Hematopoietic stem and progenitor cells (HSPCs) depend on regulatory cytokines from the marrow microenvironment. From an unbiased cytokine screen of murine marrow supernatants, we identified C-C motif chemokine ligand 5 (CCL5) as an endothelial cell-secreted hematopoietic growth factor. Following tr...

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Publicado en:Stem Cell Reports
Autores principales: Piryani, Sadhna O., Kam, Angel Y.F., Vu, Uyen T., Chao, Nelson J., Doan, Phuong L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6626871/
https://ncbi.nlm.nih.gov/pubmed/31155503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.04.023
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