Epidermal Growth Factor Regulates Hematopoietic Regeneration Following Radiation Injury

The mechanisms which regulate HSC regeneration following myelosuppressive injury are not well understood. We identified epidermal growth factor (EGF) to be highly enriched in the bone marrow (BM) serum of mice bearing deletion of Bak and Bax in Tie2(+) cells (Tie2Cre;Bak1(−/−);Bax(fl/−) mice), which...

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Bibliographic Details
Main Authors:	Doan, Phuong L., Himburg, Heather A., Helms, Katherine, Russell, J. Lauren, Fixsen, Emma, Quarmyne, Mamle, Harris, Jeffrey R., Deoliviera, Divino, Sullivan, Julie M., Chao, Nelson J., Kirsch, David G., Chute, John P.
Format:	Artigo
Language:	Inglês
Published:	2013
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3594347/ https://ncbi.nlm.nih.gov/pubmed/23377280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3070
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Epidermal Growth Factor Regulates Hematopoietic Regeneration Following Radiation Injury

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