Epidermal Growth Factor Regulates Hematopoietic Regeneration Following Radiation Injury

The mechanisms which regulate HSC regeneration following myelosuppressive injury are not well understood. We identified epidermal growth factor (EGF) to be highly enriched in the bone marrow (BM) serum of mice bearing deletion of Bak and Bax in Tie2(+) cells (Tie2Cre;Bak1(−/−);Bax(fl/−) mice), which...

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Bibliografische gegevens
Hoofdauteurs: Doan, Phuong L., Himburg, Heather A., Helms, Katherine, Russell, J. Lauren, Fixsen, Emma, Quarmyne, Mamle, Harris, Jeffrey R., Deoliviera, Divino, Sullivan, Julie M., Chao, Nelson J., Kirsch, David G., Chute, John P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594347/
https://ncbi.nlm.nih.gov/pubmed/23377280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3070
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