Loss of β-catenin triggers oxidative stress and impairs hematopoietic regeneration

Accidental or deliberate ionizing radiation exposure can be fatal due to widespread hematopoietic destruction. However, little is known about either the course of injury or the molecular pathways that regulate the subsequent regenerative response. Here we show that the Wnt signaling pathway is criti...

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Detalhes bibliográficos
Main Authors: Lento, William, Ito, Takahiro, Zhao, Chen, Harris, Jeffrey R., Huang, Wei, Jiang, Chen, Owzar, Kouros, Piryani, Sadhna, Racioppi, Luigi, Chao, Nelson, Reya, Tannishtha
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018497/
https://ncbi.nlm.nih.gov/pubmed/24788518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.231944.113
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