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Pleiotrophin regulates the expansion and regeneration of hematopoietic stem cells

Hematopoietic stem cell (HSC) self-renewal is regulated by both intrinsic and extrinsic signals. Although some of the pathways that regulate HSC self-renewal have been uncovered, it remains largely unknown whether these pathways can be triggered by deliverable growth factors to induce HSC growth or...

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Detalhes bibliográficos
Main Authors: Himburg, Heather A, Muramoto, Garrett G, Daher, Pamela, Meadows, Sarah K, Russell, J Lauren, Doan, Phuong, Chi, Jen-Tsan, Salter, Alice B, Lento, William E, Reya, Tannishtha, Chao, Nelson, Chute, John P
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689427/
https://ncbi.nlm.nih.gov/pubmed/20305662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2119
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