Role of INSL4 Signaling in Sustaining the Growth and Viability of LKB1-Inactivated Lung Cancer

BACKGROUND: The LKB1 tumor suppressor gene is commonly inactivated in non-small cell lung carcinomas (NSCLC), a major form of lung cancer. Targeted therapies for LKB1-inactivated lung cancer are currently unavailable. Identification of critical signaling components downstream of LKB1 inactivation ha...

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Pubblicato in:J Natl Cancer Inst
Autori principali: Yang, Rongqiang, Li, Steven W, Chen, Zirong, Zhou, Xin, Ni, Wei, Fu, Dongtao A, Lu, Jianrong, Kaye, Frederic J, Wu, Lizi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624166/
https://ncbi.nlm.nih.gov/pubmed/30423141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djy166
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