Role of CPS1 in Cell Growth, Metabolism, and Prognosis in LKB1-Inactivated Lung Adenocarcinoma

Background: Liver kinase B1 (LKB1) is a tumor suppressor in lung adenocarcinoma (LADC). We investigated the proteomic profiles of 45 LADC cell lines with and without LKB1 inactivation. Carbamoyl phosphate synthetase 1 (CPS1), the first rate-limiting mitochondrial enzyme in the urea cycle, was distin...

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Detalhes bibliográficos
Publicado no:J Natl Cancer Inst
Main Authors: Çeliktaş, Müge, Tanaka, Ichidai, Chandra Tripathi, Satyendra, Fahrmann, Johannes F., Aguilar-Bonavides, Clemente, Villalobos, Pamela, Delgado, Oliver, Dhillon, Dilsher, Dennison, Jennifer B., Ostrin, Edwin J., Wang, Hong, Behrens, Carmen, Do, Kim-Anh, Gazdar, Adi F., Hanash, Samir M., Taguchi, Ayumu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198847/
https://ncbi.nlm.nih.gov/pubmed/28376202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djw231
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