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Unraveling the High- and Low-Sensitivity Agonist Responses of Nicotinic Acetylcholine Receptors

The neuronal α4β2 nicotinic acetylcholine receptors exist as two distinct subtypes, (α4)(2)(β2)(3) and (α4)(3)(β2)(2), and biphasic responses to acetylcholine and other agonists have been ascribed previously to coexistence of these two receptor subtypes. We offer a novel and radical explanation for...

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Detalles Bibliográficos
Publicado en:J Neurosci
Autores principales: Harpsøe, Kasper, Ahring, Philip K., Christensen, Jeppe K., Jensen, Marianne L., Peters, Dan, Balle, Thomas
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6623092/
https://ncbi.nlm.nih.gov/pubmed/21795528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1509-11.2011
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