Molecular Recognition of the Neurotransmitter Acetylcholine by an Acetylcholine Binding Protein Reveals Determinants of Binding to Nicotinic Acetylcholine Receptors

Despite extensive studies on nicotinic acetylcholine receptors (nAChRs) and homologues, details of acetylcholine binding are not completely resolved. Here, we report the crystal structure of acetylcholine bound to the receptor homologue acetylcholine binding protein from Lymnaea stagnalis. This is t...

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Bibliografiske detaljer
Main Authors: Olsen, Jeppe A., Balle, Thomas, Gajhede, Michael, Ahring, Philip K., Kastrup, Jette S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956608/
https://ncbi.nlm.nih.gov/pubmed/24637639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091232
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