Molecular Recognition of the Neurotransmitter Acetylcholine by an Acetylcholine Binding Protein Reveals Determinants of Binding to Nicotinic Acetylcholine Receptors

Despite extensive studies on nicotinic acetylcholine receptors (nAChRs) and homologues, details of acetylcholine binding are not completely resolved. Here, we report the crystal structure of acetylcholine bound to the receptor homologue acetylcholine binding protein from Lymnaea stagnalis. This is t...

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Bibliographic Details
Main Authors: Olsen, Jeppe A., Balle, Thomas, Gajhede, Michael, Ahring, Philip K., Kastrup, Jette S.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956608/
https://ncbi.nlm.nih.gov/pubmed/24637639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091232
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