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ErbB4 promotes malignant peripheral nerve sheath tumor pathogenesis via Ras-independent mechanisms
BACKGROUND: We have found that erbB receptor tyrosine kinases drive Ras hyperactivation and growth in NF1-null malignant peripheral nerve sheath tumors (MPNSTs). However, MPNSTs variably express multiple erbB receptors with distinct functional characteristics and it is not clear which of these recep...
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| Pubblicato in: | Cell Commun Signal |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6621970/ https://ncbi.nlm.nih.gov/pubmed/31291965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0388-5 |
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