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Microglial Cathepsin B Contributes to the Initiation of Peripheral Inflammation-Induced Chronic Pain
Interleukin (IL)-1β and IL-18 play critical roles in the induction of chronic pain hypersensitivity. Their inactive forms are activated by caspase-1. However, little is known about the mechanism underlying the activation of pro-caspase-1. There is increasing evidence that cathepsin B (CatB), a typic...
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Publicado no: | J Neurosci |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Society for Neuroscience
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6621185/ https://ncbi.nlm.nih.gov/pubmed/22895716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0677-12.2012 |
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