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Microglial Cathepsin B Contributes to the Initiation of Peripheral Inflammation-Induced Chronic Pain

Interleukin (IL)-1β and IL-18 play critical roles in the induction of chronic pain hypersensitivity. Their inactive forms are activated by caspase-1. However, little is known about the mechanism underlying the activation of pro-caspase-1. There is increasing evidence that cathepsin B (CatB), a typic...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Sun, Li, Wu, Zhou, Hayashi, Yoshinori, Peters, Christoph, Tsuda, Makoto, Inoue, Kazuhide, Nakanishi, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6621185/
https://ncbi.nlm.nih.gov/pubmed/22895716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0677-12.2012
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