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The intrinsic microglial molecular clock controls synaptic strength via the circadian expression of cathepsin S

Microglia are thought to play important roles in the maintenance of neuronal circuitry and the regulation of behavior. We found that the cortical microglia contain an intrinsic molecular clock and exhibit a circadian expression of cathepsin S (CatS), a microglia-specific lysosomal cysteine protease...

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Detalhes bibliográficos
Main Authors: Hayashi, Yoshinori, Koyanagi, Satoru, Kusunose, Naoki, Okada, Ryo, Wu, Zhou, Tozaki-Saitoh, Hidetoshi, Ukai, Kiyoharu, Kohsaka, Shinichi, Inoue, Kazuhide, Ohdo, Shigehiro, Nakanishi, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783043/
https://ncbi.nlm.nih.gov/pubmed/24067868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02744
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