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Peripheral Role of Cathepsin S in Th1 Cell-Dependent Transition of Nerve Injury-Induced Acute Pain to a Chronic Pain State

There is increasing evidence that CD4(+) T-cell-dependent responses are associated with the maintenance of neuropathic pain. However, little is known about the precise mechanism(s) underlying the activation of CD4(+) T-cells. We herein show that inhibition of cathepsin S (CatS) activity, either thro...

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Detalles Bibliográficos
Publicado en:J Neurosci
Autores principales: Zhang, Xinwen, Wu, Zhou, Hayashi, Yoshinori, Okada, Ryo, Nakanishi, Hiroshi
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608526/
https://ncbi.nlm.nih.gov/pubmed/24553941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3681-13.2014
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