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Apoptosis signal-regulating kinase 1 activation by Nox1-derived oxidants is required for TNFα receptor endocytosis
Tumor necrosis factor-α (TNFα) is a proinflammatory cytokine that is closely linked to the development of cardiovascular disease. TNFα activates NADPH oxidase 1 (Nox1) and reactive oxygen species (ROS), including superoxide (O(2)(·−)), production extracellularly is required for subsequent signaling...
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| Publicat a: | Am J Physiol Heart Circ Physiol |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Physiological Society
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6620688/ https://ncbi.nlm.nih.gov/pubmed/30925081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00741.2018 |
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