Apoptosis signal-regulating kinase 1 activation by Nox1-derived oxidants is required for TNFα receptor endocytosis

Tumor necrosis factor-α (TNFα) is a proinflammatory cytokine that is closely linked to the development of cardiovascular disease. TNFα activates NADPH oxidase 1 (Nox1) and reactive oxygen species (ROS), including superoxide (O(2)(·−)), production extracellularly is required for subsequent signaling...

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Detaylı Bibliyografya
Yayımlandı:Am J Physiol Heart Circ Physiol
Asıl Yazarlar: Choi, Hyehun, Stark, Ryan J., Raja, Benjamin S., Dikalova, Anna, Lamb, Fred S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620688/
https://ncbi.nlm.nih.gov/pubmed/30925081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00741.2018
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