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Sex-specific differences in emphysema using a murine antisense oligonucleotide model of α-1 antitrypsin deficiency
α-1 Antitrypsin (AAT) deficiency is the leading genetic cause of emphysema; however, until recently, no genuine animal models of AAT deficiency existed, hampering the development of new therapies. This shortcoming is now addressed by both AAT-null and antisense oligonucleotide mouse models. The goal...
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| Publicado en: | Am J Physiol Lung Cell Mol Physiol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Physiological Society
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6620672/ https://ncbi.nlm.nih.gov/pubmed/31017014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00502.2018 |
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