Role for Cela1 in Postnatal Lung Remodeling and Alpha-1 Antitrypsin–Deficient Emphysema

Alpha-1 antitrypsin (AAT) deficiency–related emphysema is the fourth leading indication for lung transplant. Chymotrypsin-like elastase 1 (Cela1) is a digestive protease that is expressed during lung development in association with regions of elastin remodeling, exhibits stretch-dependent expression...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Joshi, Rashika, Heinz, Andrea, Fan, Qiang, Guo, Shuling, Monia, Brett, Schmelzer, Christian E. H., Weiss, Anthony S., Batie, Matthew, Parameshwaran, Harikrishnan, Varisco, Brian M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096338/
https://ncbi.nlm.nih.gov/pubmed/29420065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2017-0361OC
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