Elevated intracellular trypsin exacerbates acute pancreatitis and chronic pancreatitis in mice

Intra-acinar trypsinogen activation occurs in the earliest stages of pancreatitis and is believed to play important roles in pancreatitis pathogenesis. However, the exact role of intra-acinar trypsin activity in pancreatitis remains elusive. Here, we aimed to examine the specific effects of intra-ac...

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Опубликовано в: :Am J Physiol Gastrointest Liver Physiol
Главные авторы: Zhan, Xianbao, Wan, Jianhua, Zhang, Guowei, Song, Lele, Gui, Fu, Zhang, Yuebo, Li, Yinghua, Guo, Jia, Dawra, Rajinder K., Saluja, Ashok K., Haddock, Ashley N., Zhang, Lizhi, Bi, Yan, Ji, Baoan
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2019
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620583/
https://ncbi.nlm.nih.gov/pubmed/30943050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00004.2019
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