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Caerulein-Induced Chronic Pancreatitis Does Not Require Intra-Acinar Activation of Trypsinogen in Mice

BACKGROUND & AIMS: Premature activation of trypsinogen activation can cause pancreatic injury and has been associated with chronic pancreatitis (CP). Mice that lack intra-acinar activation of trypsinogen, such as trypsinogen-7–null (T−/−) and cathepsin B-null (CB−/−) mice, have been used to stud...

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Detalhes bibliográficos
Main Authors: Sah, Raghuwansh P, Dudeja, Vikas, Dawra, Rajinder K, Saluja, Ashok K
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928043/
https://ncbi.nlm.nih.gov/pubmed/23354015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.01.041
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