Nelfinavir/ritonavir reduces acinar injury but not inflammation during mouse caerulein pancreatitis

There is no clinical treatment that reduces acinar injury during pancreatitis. Human immunodeficiency virus (HIV) protease inhibitors (PI), including nelfinavir (NFV) and ritonavir (RTV), may reduce the rate of pancreatitis in HIV-infected patients. Since permeability transition pore (PTPC)-mediated...

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Autori principali: Singh, Vijay P., Bren, Gary D., Algeciras-Schimnich, Alicia, Schnepple, David, Navina, Sarah, Rizza, Stacey A., Dawra, Rajinder K., Saluja, Ashok K., Chari, Suresh T., Vege, Santhi S., Badley, Andrew D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2009
Soggetti:
Inflammation/Immunity/Mediators
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696210/
https://ncbi.nlm.nih.gov/pubmed/19282375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90642.2008
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