Nelfinavir/ritonavir reduces acinar injury but not inflammation during mouse caerulein pancreatitis

There is no clinical treatment that reduces acinar injury during pancreatitis. Human immunodeficiency virus (HIV) protease inhibitors (PI), including nelfinavir (NFV) and ritonavir (RTV), may reduce the rate of pancreatitis in HIV-infected patients. Since permeability transition pore (PTPC)-mediated...

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Autors principals: Singh, Vijay P., Bren, Gary D., Algeciras-Schimnich, Alicia, Schnepple, David, Navina, Sarah, Rizza, Stacey A., Dawra, Rajinder K., Saluja, Ashok K., Chari, Suresh T., Vege, Santhi S., Badley, Andrew D.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2009
Matèries:
Inflammation/Immunity/Mediators
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696210/
https://ncbi.nlm.nih.gov/pubmed/19282375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90642.2008
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