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Caerulein-Induced Chronic Pancreatitis Does Not Require Intra-Acinar Activation of Trypsinogen in Mice
BACKGROUND & AIMS: Premature activation of trypsinogen activation can cause pancreatic injury and has been associated with chronic pancreatitis (CP). Mice that lack intra-acinar activation of trypsinogen, such as trypsinogen-7–null (T−/−) and cathepsin B-null (CB−/−) mice, have been used to stud...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3928043/ https://ncbi.nlm.nih.gov/pubmed/23354015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.01.041 |
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