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Acute increases in O-GlcNAc indirectly impair mitochondrial bioenergetics through dysregulation of LonP1-mediated mitochondrial protein complex turnover
The attachment of O-linked β-N-acetylglucosamine (O-GlcNAc) to the serine and threonine residues of proteins in distinct cellular compartments is increasingly recognized as an important mechanism regulating cellular function. Importantly, the O-GlcNAc modification of mitochondrial proteins has been...
Shranjeno v:
| izdano v: | Am J Physiol Cell Physiol |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Physiological Society
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6620580/ https://ncbi.nlm.nih.gov/pubmed/30865517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00491.2018 |
| Oznake: |
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