O-GlcNAc regulation of autophagy and α-synuclein homeostasis; implications for Parkinson’s disease

Post-translational modification on protein Ser/Thr residues by O-linked attachment of ß-N-acetyl-glucosamine (O-GlcNAcylation) is a key mechanism integrating redox signaling, metabolism and stress responses. One of the most common neurodegenerative diseases that exhibit aberrant redox signaling, met...

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Publicado en:Mol Brain
Autores principales: Wani, Willayat Y., Ouyang, Xiaosen, Benavides, Gloria A., Redmann, Matthew, Cofield, Stacey S., Shacka, John J., Chatham, John C., Darley-Usmar, Victor, Zhang, Jianhua
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5517830/
https://ncbi.nlm.nih.gov/pubmed/28724388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-017-0311-1
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