Enhanced Microbial Bile Acid Deconjugation and Impaired Ileal Uptake in Pregnancy Repress Intestinal Regulation of Bile Acid Synthesis

Pregnancy is associated with progressive hypercholanemia, hypercholesterolemia, and hypertriglyceridemia, which can result in metabolic disease in susceptible women. Gut signals modify hepatic homeostatic pathways, linking intestinal content to metabolic activity. We sought to identify whether enter...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Ovadia, Caroline, Perdones‐Montero, Alvaro, Spagou, Konstantina, Smith, Ann, Sarafian, Magali H., Gomez‐Romero, Maria, Bellafante, Elena, Clarke, Louise C.D., Sadiq, Fouzia, Nikolova, Vanya, Mitchell, Alice, Dixon, Peter H., Santa‐Pinter, Natalie, Wahlström, Annika, Abu‐Hayyeh, Shadi, Walters, Julian R.F., Marschall, Hanns‐Ulrich, Holmes, Elaine, Marchesi, Julian R., Williamson, Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619257/
https://ncbi.nlm.nih.gov/pubmed/30983011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30661
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